KMID : 0032220090210020178
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Annals of Dermatology 2009 Volume.21 No. 2 p.178 ~ p.181
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Vitiligo-Like Depigmentation Associated with Metastatic Melanoma of an Unknown Origin
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Cho Eun-Ah
Lee Myung-Ah Kang Hoon Lee Seung-Dong Kim Hyung-Ok Park Young-Min
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Abstract
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Although malignant melanoma usually occurs after the diagnosis of vitiligo-like depigmentation, the latter is rarely followed by the former. We herein report on such a case in which recognition of the vitiligo-like depigmentation preceded diagnosing the metastatic melanoma by several months. A 56-year-old woman had first developed vitiligo-like depigmentation on the forehead, eyelids, neck and back 18 months previously and thereafter she detected a hard mass in the left axilla 2 months previously. Based on the histologic findings, the axillary mass was diagnosed as metastatic melanoma. To evaluate the primary tumor focus, thorough examinations that included PET-CT, bone scan and sigmoidoscopy were performed, but we couldn`t find any the original primary tumor. Our case suggests that the vitiligo-like depigmentation could be a sign that heralds metastatic melanoma.
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KEYWORD
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Metastatic melanoma, Vitiligo-Like depigmentation
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